What is Corona Virus/COVID 19?
COVID–19 is a new disease that has been
detected in the human body, and no previous case of COVID–19 pneumonia has been
discovered. The chief clinical symptoms of those infected with coronavirus are
coldness, severe acute respiratory syndrome (SARS) and Middle East respiratory
syndrome (MERS).
The
signs and symptoms of the person infected are:
- Fever
- Cough
- Shortness
of breath
There are certain emergency signs such as:
- Difficulty breathing or
shortness of breath
- Persistent pain or pressure
in the chest
- New confusion or inability
to arouse
- Bluish lips or face
If you develop symptoms, seek medical advice.
Biomarkers for COVID 19
Two Parameters that may serve as a potential biomarker
for COVID-19 are Various blood parameters and CRP.
The significant differences in the ratios between
various blood parameters and CRP between the two groups are interesting
findings in a study. It has been seen that CRP may not or only slightly
increase in viral infection without bacterial infection. This increase
indirectly reflects the severity of the infection. At present, it is generally
accepted that CRP or combined CRP can be used to judge the inflammatory
activity.
In this study, we found that the ratio between various
blood parameters and CRP was significantly increased in patients who had
indirect contact with the disease in the epidemic area, suggesting that the
change in the reactivity of CRP in COVID–19 infection is greater than the response of various blood parameters.
In addition, considering that COVID–19 in the secondary the epidemic area may occur after the primary epidemic in the main epidemic area,
its toxicity and pathogenicity may be weakened. CRP can be used as a predictive
factor prior to changes in leukocytes, lymphocytes, neutrophils and other
inflammatory-related blood parameters to comprehensively evaluate the
occurrence and development of COVID–19 infection.
CVD (Cardiovascular Diseases) and
COVID 19
The virus ‘Severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2)’ (the scientific name of the virus infects the host
cells through ACE2 receptors, resulting in coronavirus disease
(COVID-19)-related pneumonia, it also causes acute myocardial injury and
chronic damage to the circulatory system. Hence, particular attention should
tend to cardiovascular protection during treatment for COVID-19.
Angiotensin-converting
enzyme 2 (ACE2) may be a membrane-bound aminopeptidase that features a vital
role within the cardiovascular and immune systems. ACE2 is involved in heart
function and therefore the development of hypertension and DM. In addition,
ACE2 has been identified as a functional receptor for coronaviruses, including
SARS-CoV and SARS-CoV-2. SARS-CoV-2 infection is triggered by binding of the
spike protein of the virus to ACE2, which is very expressed within the heart
and lungs.
SARS-CoV-2 mainly
invades alveolar epithelial cells, leading to respiratory symptoms. These
symptoms are more severe in patients with CVD, which could be related to
increased secretion of ACE2 in these patients compared with healthy
individuals. ACE2 levels are often increased by the utilization of
renin-angiotensin-aldosterone system inhibitors.
Given that ACE2 may be a
functional receptor for SARS-CoV-2, the security and potential effects of
anti-hypertension therapy with ACE inhibitors or angiotensin-receptor blockers
in patients with COVID-19 should be carefully considered.
The COVID-19 virus, although not as lethal as SARS, has
proved far more pervasive. It took but two months from the invention of the
primary infection for the number of confirmed cases to pass the entire that
SARS reached over several months. And in three months, COVID-19 has killed
quite five times as many of us as SARS.
Precautions
- Wash your hands often with soap and water for a minimum of 20
seconds
- · If soap and water aren't readily available, use a hand sanitizer
that contains a minimum of 60% alcohol.
- · Avoid touching your eyes, nose, and mouth with unwashed hands.
- · Avoid close contact with folks that are sick.
- · Put distance between yourself and people if COVID-19 is spreading
in your community.
- · Stay home if you're sick, except to urge medical aid
- · Cover your mouth and nose with a tissue once you cough or sneeze or use the within of your elbow.
